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Triprolidine: Wikis


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Systematic (IUPAC) name
CAS number 486-12-4
ATC code R06AX07
PubChem 5282443
DrugBank APRD00306
Chemical data
Formula C 19H22N2  
Mol. mass 278.391 g/mol
SMILES eMolecules & PubChem
Physical data
Melt. point 60 °C (140 °F)
Solubility in water 500 mg/mL (20 °C)
Pharmacokinetic data
Bioavailability 4% oral
Protein binding 90%
Metabolism Hepatic (CYP2D6)
Half life 4-6 hours
Excretion Renal
Therapeutic considerations
Pregnancy cat. C (US)
Legal status OTC (US)
Routes Oral
 Yes check.svgY(what is this?)  (verify)

Triprolidine (Actidil, Myidil) is an over-the-counter antihistamine with anticholinergic properties. It is used to combat the symptoms associated with allergies and is sometimes combined with other cold medications designed to provide general relief for flu-like symptoms. Like many over-the-counter antihistamines, the most common side effect is drowsiness. Triprolidine is a quick acting drug that can clear congestion and stop runny noses in 15-30 minutes.


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