The Full Wiki

Triprolidine: Wikis

  

Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.

Encyclopedia

From Wikipedia, the free encyclopedia

Triprolidine
Systematic (IUPAC) name
2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-yl-
prop-1-enyl]pyridine
Identifiers
CAS number 486-12-4
ATC code R06AX07
PubChem 5282443
DrugBank APRD00306
Chemical data
Formula C 19H22N2  
Mol. mass 278.391 g/mol
SMILES eMolecules & PubChem
Physical data
Melt. point 60 °C (140 °F)
Solubility in water 500 mg/mL (20 °C)
Pharmacokinetic data
Bioavailability 4% oral
Protein binding 90%
Metabolism Hepatic (CYP2D6)
Half life 4-6 hours
Excretion Renal
Therapeutic considerations
Pregnancy cat. C (US)
Legal status OTC (US)
Routes Oral
 Yes check.svgY(what is this?)  (verify)

Triprolidine (Actidil, Myidil) is an over-the-counter antihistamine with anticholinergic properties. It is used to combat the symptoms associated with allergies and is sometimes combined with other cold medications designed to provide general relief for flu-like symptoms. Like many over-the-counter antihistamines, the most common side effect is drowsiness. Triprolidine is a quick acting drug that can clear congestion and stop runny noses in 15-30 minutes.

References








Got something to say? Make a comment.
Your name
Your email address
Message