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Tropheryma whipplei
Scientific classification
Kingdom: Bacteria
Phylum: Actinobacteria
Class: Actinobacteria
Subclass: Actinobacteridae
Order: Actinomycetales
Genus: Tropheryma
Species: T. whipplei
Binomial name
Tropheryma whipplei
La Scola et al. 2001

Tropheryma whipplei, formerly called Tropheryma whippelii,[1] is a bacterium and the causative organism of Whipple's disease.[2]

While T. whipplei is categorized with the Gram-positive Actinobacteria, the organism is commonly found to be Gram-negative or Gram-indeterminate when stained in the laboratory.[2] Whipple himself probably observed the organisms as rod-shaped structures with silver stain in his original case.[3]

History of the name

No name was given to the organism until 1991 when the name Tropheryma whippelii was proposed after sections of the bacterial genome were sequenced.[4] The name was changed to Tropheryma whipplei in 2001 (correcting the spelling of Whipple's name) after deposition in bacterial collections.[2]



  1. ^ Liang Z, La Scola B, Raoult D (January 2002). "Monoclonal antibodies to immunodominant epitope of Tropheryma whipplei". Clin. Diagn. Lab. Immunol. 9 (1): 156–9. doi:10.1128/CDLI.9.1.156-159.2002. PMID 11777846. PMC 119894.  
  2. ^ a b c La Scola B, Fenollar F, Fournier PE, Altwegg M, Mallet MN, Raoult D (July 2001). "Description of Tropheryma whipplei gen. nov., sp. nov., the Whipple's disease bacillus". Int. J. Syst. Evol. Microbiol. 51 (Pt 4): 1471–9. PMID 11491348.  
  3. ^ Whipple GH. (1907). "A hitherto undescribed disease characterized anatomically by deposits of fat and fatty acids in the intestinal and mesenteric lymphatic tissues". Johns Hopkins Hosp Bull 18: 382–91.  
  4. ^ Relman D, Schmidt T, MacDermott R, Falkow S (1992). "Identification of the uncultured bacillus of Whipple's disease". N Engl J Med 327 (5): 293–301. PMID 1377787.  


Up to date as of January 23, 2010

From Wikispecies


Main Page
Superregnum: Bacteria
Regnum: Bacteria
Phylum: Actinobacteria
Classis: Actinobacteria
Subclassis: Actinobacteridae
Ordo: Actinomycetales
Subordo: Micrococcineae
Familia: Cellulomonadaceae
Genus: Tropheryma
Species: Tropheryma whipplei


Tropheryma B. La Scola, F. Fenollar, P.E. Fournier, M. Altwegg, M.N. Mallet & D. Raoult, 2001


  • Description of Tropheryma whipplei gen. nov., sp. nov., the Whipple's disease bacillus. Int. J. Syst. Evol. Microbiol., 2001, 51, 1471-1479.


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