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Two-pore channel: Wikis

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two pore segment channel 1
Identifiers
Symbol TPCN1
IUPHAR TPC1
Entrez 53373
HUGO 18182
OMIM 609666
RefSeq NM_017901
UniProt Q9ULQ1
Other data
Locus Chr. 12 q24.21
two pore segment channel 2
Identifiers
Symbol TPCN2
IUPHAR TPC2
Entrez 219931
HUGO 20820
RefSeq NM_139075
UniProt Q8NHX9
Other data
Locus Chr. 11 q13.1

Two-pore channels: This small family of 2 members putatively forms cation-selective ion channels. They are predicted to contain two KV-style six-transmembrane domains, suggesting they form a dimer in the membrane. These channels are closely related to CatSper channels and, more distantly, to TRP channels.

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