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University of Mississippi Medical Center (UMC) is the health sciences campus of the University of Mississippi (Ole Miss) and is located in Jackson, Mississippi.

UMC houses the University of Mississippi School of Medicine, University of Mississippi Medical Center School of Dentistry, Nursing, Health Related Professions, and Graduate Studies in the Health Sciences.

UMC is also home to the University Hospital and Clinics, a 722-bed tertiary care facility providing about 27,000 inpatient visits and 418,000 outpatient and emergency visits each year.

On the Medical Center campus, the University Hospitals and Health System includes the University Hospital, Winfred L. Wiser Hospital for Women & Infants, Blair E. Batson Hospital for Children and, for faculty practice, the University Medical Pavilion.

The university is the only hospital in the state designated as a level 1 trauma center. Specialized hospital services include: an interventional MRI; the only level 3 neonatal intensive care unit (NICU) in the state; separate medical, surgical, cardiac, neuroscience and pediatric ICUs; a heart station for diagnosis and treatment of heart disease; a heart failure clinic; heart, kidney, cornea and bone marrow transplant programs; a comprehensive stroke unit; state-of-the-art radiological imaging systems; a sleep disorders laboratory; an in vitro fertilization program; and special pharmaceutical services.

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