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Urapidil
Systematic (IUPAC) name
6-({3-[4-(2-methoxyphenyl) piperazin-1-yl] propyl}amino)- 1,3-dimethylpyrimidine- 2,4(1H,3H)- dione
Identifiers
CAS number 34661-75-1
ATC code C02CA06
PubChem 5639
Chemical data
Formula C 20H29N5O3  
Mol. mass 387.48 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Urapidil is a sympatholytic antihypertensive drug. It functions as an α1-adrenergic receptor antagonist, α2-adrenergic receptor agonist, and 5-HT1A receptor agonist.[1] Urapidil is currently not approved by the U.S. Food and Drug Administration, but it is available in Europe.

References

  1. ^ Ramage AG (April 1991). "The mechanism of the sympathoinhibitory action of urapidil: role of 5-HT1A receptors". Br. J. Pharmacol. 102 (4): 998–1002. PMID 1855130.  
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