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Ureaplasma urealyticum
Scientific classification
Kingdom: Bacteria
Division: Firmicutes
Class: Mollicutes
Order: Mycoplasmatales
Family: Mycoplasmataceae
Genus: Ureaplasma
Species: U. urealyticum
Binomial name
Ureaplasma urealyticum
Shepard et al., 1974

Ureaplasma urealyticum is a bacterium belonging to the family Mycoplasmataceae. Its type strain is T960.


Clinical significance

U. urealyticum is part of the normal genital flora of both men and women. It is found in about 70% of sexually active humans.

It had also been described to be associated with a number of diseases in humans, including non-specific urethritis (NSU), infertility, chorioamnionitis, stillbirth, premature birth, and, in the perinatal period, pneumonia, bronchopulmonary displasia[1] and meningitis.

However, given the relatively low pathogenicity of the organism its role in some of these diseases remains contentious.


There are six recognised Ureaplasma species, They have a GC content of 27-30%, and a genome size ranging between 0.76-1.17 Mbp, and cholesterol is required for growth. A defining characteristic of the genus is that they perform urea hydrolysis.

It is now recommended that some strains originally classified as Ureaplasma urealyticum should be treated as a new species, U. parvum.


Ureaplasma can come and go, doesn't cause permanent damage and should be cleared up with a day 10 treatment of doxycycline for both partners.

Penicillin is ineffective -- these bacteria don't have a cell wall, which is the target of penicillin.


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