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VUF-8430: Wikis

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VUF-8430
VUF-8430 structure.png
IUPAC name
Identifiers
CAS number 98021-17-1
SMILES
Properties
Molecular formula C4H11N5S
Molar mass 161.228 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

VUF-8430 is a histamine agonist[1] selective for the H4 subtype.[2]

References

  1. ^ Smith FM, Haskelberg H, Tracey DJ, Moalem-Taylor G (2007). "Role of histamine H3 and H4 receptors in mechanical hyperalgesia following peripheral nerve injury". Neuroimmunomodulation 14 (6): 317–25. doi:10.1159/000125048. PMID 18401194. http://content.karger.com/produktedb/produkte.asp?typ=fulltext&file=000125048.  
  2. ^ Lim HD, Smits RA, Bakker RA, van Dam CM, de Esch IJ, Leurs R. Discovery of S-(2-guanidylethyl)-isothiourea (VUF 8430) as a potent nonimidazole histamine H4 receptor agonist. Journal of Medicinal Chemistry. 2006 Nov 16;49(23):6650-1. PMID 17154494
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