From Wikipedia, the free encyclopedia
Vaccenic acid is a naturally occurring trans fat found in the fat
of ruminants and in dairy products such
as milk and yogurt. It is
also the predominant 'trans-fat' in human milk.
name is (E)-11-octadecenoic acid, and its lipid shorthand
name is 18:1 trans-11. The name was derived from the Latin vacca (cow).
Vaccenic acid was discovered in 1928 in animal fats and butter. It is the main trans fatty acid
isomer present in milk fat.
Mammals convert it into rumenic acid, a conjugated linoleic acid,
where it shows anticarcinogenic properties.
Its stereoisomer, cis-vaccenic acid is an omega-7
fatty acid found in Sea Buckthorn
(Hippophae rhamnoides) oil.
name is (Z)-11-octadecenoic acid, and its lipid shorthand
name is 18:1 cis-11.
A 2008 study at the University of Alberta suggests
that vaccenic acid feeding in rats over 16 weeks resulted in
lowered total cholesterol, lowered LDL cholesterol and lower triglyceride levels.
The researchers are preparing to conduct further research,
including human clinical trials.
It has been suggested that the oxidative degradation of omega-7 unsaturated fatty
acids on the skin surface, such as palmitoleic acid and vaccenic acid,
may be the cause of the phenomenon commonly known as old person smell.
Natural trans fats may be
good for you. May 19, 2008
Precht, D and J.Molkentin C18:1, C18:2, and C8:3 trans and cis
fatty acid isomers including conjugated cis delta 9, trans delta 11
linoleic acid (CLA) as well as total fat composition of German
human milk lipids, Nahrung 1999 43(4) 233-244
Friesen, R, and S.M. Innis, Trans Fatty acids in Human milk in
Canada declined with the introduction of trans fat food labeling,
J. Nut 2006, 136 2558-2561
- ^ a
F. Destaillats, E. Buyukpamukcu,
P.-A. Golay, F. Dionisi and F. Giuffrida (2005). "Letter to the
Editor: Vaccenic and Rumenic Acids, A Distinct Feature of Ruminant
Fats". J. Dairy Sci 88 (449).
- ^ Bauman, Dale. "cis-9, trans-11 CLA - A
Potent Anticarcinogen Found in Milk Fat". http://www.ansci.cornell.edu/bauman/human_health/index.htm. Retrieved
- ^ Banni S, Angioni E, Murru E, Carta G,
Melis M, Bauman D, Dong Y, Ip C (2001). "Vaccenic acid feeding
increases tissue levels of conjugated linoleic acid and suppresses
development of premalignant lesions in rat mammary gland". Nutr
Cancer 41 (1-2): 91–7. doi:10.1207/S15327914NC41-1&2_12. PMID 12094634.
- ^ Lock AL, Corl BA, Barbano DM, Bauman DE,
Ip C. (October 1, 2004). "The anticarcinogenic effect
of trans-11 18:1 is dependent on its conversion to cis-9, trans-11
CLA by delta9-desaturase in rats". J Nutr
134(10) (10): 2698–704. PMID 15465769. http://jn.nutrition.org/cgi/content/abstract/134/10/2698. Retrieved
- ^ Federal Research Centre for Nutrition and Food
- Institute for Lipid Research. "Seed Oil Fatty Acids
AFNS. Alberta natural trans fat
research earns global recognition. Apr 2, 2008.
S. Haze, Y. Gozu, S. Nakamura, Y.
Kohno, K. Sawano, H. Ohta and K. Yamazaki (2001). "2-Nonenal Newly
Found in Human Body Odor Tends to Increase with Aging". Journal of
Investigative Dermatology 116 (4):