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Vibrio cholerae
TEM image
Scientific classification
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Gamma Proteobacteria
Order: Vibrionales
Family: Vibrionaceae
Genus: Vibrio
Species: V. cholerae
Binomial name
Vibrio cholerae
Pacini 1854

Vibrio cholerae (also Kommabacillus) is a gram negative comma shaped bacterium with a polar flagellum that causes cholera in humans.[1][2] V. cholerae and other species of the genus Vibrio belong to the gamma subdivision of the Proteobacteria.  

There are two major biotypes of V. cholerae, classical and El Tor, and numerous other serogroups.

V. cholerae was first isolated as the cause of cholera by Italian anatomist Filippo Pacini in 1854, but his discovery was not widely known until Robert Koch, working independently thirty years later, publicized the knowledge and the means of fighting the disease.


Genomics and Evolution

The 4.0 Mbp genome of N16961, an O1 serogroup, (in America) El Tor biotype, 7th pandemic strain of V. cholerae, is composed of two circular chromosomes of unequal size that are predicted to encode a total of 3,885 genes[3]. The genomic sequence of this representative strain has furthered our understanding of the genetic and phenotypic diversity found within the species V. cholerae. Sequence data have been used to identify horizontally acquired sequences, dissect complex regulatory and signaling pathways, and develop computational approaches to predict patterns of gene expression and the presence of metabolic pathway components. Microarrays are being used to study the evolution of the organism. Genomic sequencing of additional strains, subtractive hybridization studies and the introduction of new model systems have also contributed to the identification of novel sequences and pathogenic mechanisms associated with other strains.[2]

See also


  1. ^ Ryan KJ; Ray CG (editors) (2004). Sherris Medical Microbiology (4th ed. ed.). McGraw Hill. ISBN 0838585299.  
  2. ^ a b Faruque SM; Nair GB (editors). (2008). Vibrio cholerae: Genomics and Molecular Biology. Caister Academic Press. ISBN 978-1-904455-33-2 .  
  3. ^ Heidelberg, et al. (2000). DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae. Nature 406(6795):477-83

External links


Up to date as of January 23, 2010

From Wikispecies

Vibrio cholerae


Main Page
Superregnum: Bacteria
Regnum: Bacteria
Phylum: Proteobacteria
Classis: Gamma Proteobacteria
Ordo: Vibrionales
Familia: Vibrionaceae
Genus: Vibrio
Species: Vibrio cholerae
Strain: Vibrio cholerae 569B - Vibrio cholerae O139 - Vibrio cholerae non-O1 - Vibrio cholerae O1 - Vibrio cholerae non-O1/non-O139 - Vibrio cholerae O27 - Vibrio cholerae O37 - Vibrio cholerae MO10 - Vibrio cholerae O395 - Vibrio cholerae RC385 - Vibrio cholerae V51 - Vibrio cholerae V52 - Vibrio cholerae bv. albensis - Vibrio cholerae AM-19226 - Vibrio cholerae 2740-80 - Vibrio cholerae MZO-3 - Vibrio cholerae 1587 - Vibrio cholerae MAK 757 - Vibrio cholerae 623-39 - Vibrio cholerae MZO-2 - Vibrio cholerae NCTC 8457 - Vibrio cholerae B33 - Vibrio cholerae O26 - Vibrio cholerae M66-2 - Vibrio cholerae 12129(1) - Vibrio cholerae TM 11079-80 - Vibrio cholerae BX 330286 - Vibrio cholerae RC9 - Vibrio cholerae TMA 21 - Vibrio cholerae VC-11E03 - Vibrio cholera CIRS 101 - Vibrio cholerae Ind5 - Vibrio cholerae Ban5 -


Vernacular names

English: Kommabacillus

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