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Viqualine
Systematic (IUPAC) name
4-[3-[(3R,4R)-3-ethenylpiperidin-4-yl]propyl]-6-methoxyquinoline
Identifiers
CAS number 72714-74-0
ATC code  ?
PubChem 51669
Chemical data
Formula C 20H26N2O 
Mol. mass 310.432 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Viqualine (PK-5078) is a psychoactive drug and research chemical of the quinoline chemical class that possesses antidepressant and anxiolytic properties.[1] It acts as a selective serotonin releasing agent (SSRA).[2] It has mainly been researched as a potential treatment for alcoholism.[3][4]

References

  1. ^ Faravelli C, Albanesi G, Sessarego A (1988). "Viqualine in resistant depression: a double-blind, placebo-controlled trial". Neuropsychobiology 20 (2): 78–81. PMID 3075725.  
  2. ^ Le Fur G, Imbault F, Mitrani N, Marquis F, Renault C, Dubroeucq MC, Gueremy C, Uzan A (February 1984). "The 5-hydroxytryptamine-releasing properties of two epimer quinoline derivatives". Neuropharmacology 23 (2A): 169–73. PMID 6717757.  
  3. ^ Naranjo CA, Sellers EM (1989). "Serotonin uptake inhibitors attenuate ethanol intake in problem drinkers". Recent Developments in Alcoholism : an Official Publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism 7: 255–66. PMID 2522667.  
  4. ^ Naranjo CA, Sullivan JT, Kadlec KE, Woodley-Remus DV, Kennedy G, Sellers EM (September 1989). "Differential effects of viqualine on alcohol intake and other consummatory behaviors". Clinical Pharmacology and Therapeutics 46 (3): 301–9. PMID 2673621.  







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