The Full Wiki

Vitreous humour: Wikis

Advertisements
  

Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.

Encyclopedia

From Wikipedia, the free encyclopedia

Vitreous humour
Schematic diagram of the human eye en.svg
Schematic diagram of the human eye.
Latin humor vitreus

The vitreous humour (British spelling) or vitreous humor (US spelling) is the clear gel that fills the space between the lens and the retina of the eyeball of humans and other vertebrates. It is often referred to as the vitreous body or simply "the vitreous".

Contents

Composition, properties and function

The vitreous is the transparent, colourless, gelatinous mass that fills the space between the lens of the eye and the retina lining the back of the eye. It is produced by certain retinal cells. It is of rather similar composition to the cornea, but contains very few cells (mostly phagocytes which remove unwanted cellular debris in the visual field, as well as the hyalocytes of Balazs of the surface of the vitreous, which reprocess the hyaluronic acid), no blood vessels, and 98-99% of its volume is water (as opposed to 75% in the cornea) with salts, sugars, vitrosin (a type of collagen), a network of collagen type II fibers with the mucopolysaccharide hyaluronic acid, and also a wide array of proteins in micro amounts. Amazingly, with so little solid matter, it tautly holds the eye. The lens, on the other hand, is tightly packed with cells.[1] However, the vitreous has a viscosity two to four times that of pure water, giving it a gelatinous consistency. It also has a refractive index of 1.336[2].

Although the vitreous is in contact with the retina and helps to keep it in place by pressing it against the choroid, it does not adhere to the retina, except in three places: around the anterior border of the retina; in the macula, the tiny spot in the retina which gives us our "detail" and central vision; and at the optic nerve disc (where the retina sends about 1.2 million nerve fibres (axons) to the brain).

Unlike the fluid in the frontal parts of the eye (aqueous humour) which is continuously replenished, the gel in the vitreous chamber is stagnant. Therefore, if blood, cells or other byproducts of inflammation get into the vitreous, they will remain there unless removed surgically[citation needed] (see floaters). If the vitreous pulls away from the retina, it is known as a vitreous detachment. As we age, the vitreous often liquefies and may collapse. This is more likely to occur, and occurs much earlier, in eyes that are nearsighted (myopia). It can also occur after injuries to the eye or inflammation in the eye (uveitis).

Pathology

The collagen fibres of the vitreous are held apart by electrical charges. With ageing, these charges tend to reduce, and the fibres may clump together. Similarly, the gel may liquefy, a condition known as syneresis, allowing cells and other organic clusters to float freely within the vitreous humour. These allow floaters which are perceived in the visual field as spots or fibrous strands. Floaters are generally harmless, but the sudden onset of recurring floaters may signify a posterior vitreous detachment (PVD) or other diseases of the eye.

Clinical significance

The metabolic exchange and equilibration between systemic circulation and vitreous humour is so slow that vitreous humour is sometimes the fluid of choice for postmortem analysis of glucose levels or substances which would be more rapidly diffused, degraded, excreted, or metabolized from the general circulation.

External links

References

  1. ^ "eye, human."Encyclopædia Britannica from Encyclopædia Britannica 2006 Ultimate Reference Suite DVD 2009
  2. ^ The Vitreous Humor
Advertisements

Advertisements






Got something to say? Make a comment.
Your name
Your email address
Message