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WAY-213,613: Wikis


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Systematic (IUPAC) name
(2S)-2-amino-4-[4-(2-bromo-4,5-difluorophenoxy)anilino]-4-oxobutanoic acid
CAS number 868359-05-1
ATC code  ?
PubChem 11531745
Chemical data
Formula C 16H13BrF2N2O4  
Mol. mass 415.186 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

WAY-213,613 is a drug which acts as a reuptake inhibitor for the glutamate transporter subtype EAAT2, selective over other glutamate transporter subtypes and highly selective over metabotropic and ionotropic glutamate receptors.[1] It is used in scientific research into the function of the glutamate transporters.[2]


  1. ^ Dunlop J, McIlvain HB, Carrick TA, Jow B, Lu Q, Kowal D, Lin S, Greenfield A, Grosanu C, Fan K, Petroski R, Williams J, Foster A, Butera J. Characterization of novel aryl-ether, biaryl, and fluorene aspartic acid and diaminopropionic acid analogs as potent inhibitors of the high-affinity glutamate transporter EAAT2. Molecular Pharmacology. 2005 Oct;68(4):974-82. PMID 16014807
  2. ^ Karatas-Wulf U, Koepsell H, Bergert M, Sönnekes S, Kugler P. Protein kinase C-dependent trafficking of glutamate transporters excitatory amino acid carrier 1 and glutamate transporter 1b in cultured cerebellar granule cells. Neuroscience. 2009 Jul 7;161(3):794-805. PMID 19364521


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