From Wikipedia, the free encyclopedia
Werner Theodor Otto Forßmann, (August 29, 1904
– June 1, 1979) was a physician from Germany who won the Nobel Prize in Medicine for developing a
procedure that allowed for the catheterization of the heart.
Life
Forßmann was born in Berlin
on August 29, 1904. Upon graduating from Askanische Gymnasium, he
entered the University of
Berlin to study medicine, passing the State Examination in
1929.[1]
He hypothesized that a catheter could be inserted directly into
the heart, for such applications as directly delivering drugs,
injecting radiopaque
dyes, or measuring blood pressure. The fear at the time was that
such an intrusion into the heart would be fatal.[2]
In order to prove his point, he decided to try the experiment on
himself.
In 1929, while working in Eberswalde, he performed the first human cardiac catheterization. He
ignored his department chief and tied his assistant to an operating
table.[3]
Then, he anesthetized his own lower arm and inserted a cannula into his antecubital
vein, threading it 65 cm all the way to his heart.[1]
Afterwards, he walked some distance to the X-ray department to
photograph the catheter which was now lying in his right
atrium.
The head clinician at Eberswalde, recognizing Werner's
discovery, created an unpaid position for him at the Berliner Charité Hospital,
working under Ferdinand Sauerbruch. Though, once
Sauerbruch saw his paper, he was thrown out of the hospital.
Sauerbruch commented, "You certainly can't begin surgery in that
manner".[4]
Facing such disciplinary action for self-experimentation, he was
forced to quit cardiology and take up urology.[2]
He left to work at City Hospital at Mainz. And then, went to
study urology under Karl Heusch at the Rudolf Virchow Hospital in
Berlin. Later, he was
appointed Chief of the Surgical Clinic at both the City Hospital at
Dresden-Friedrichstadt and the Robert Koch Hospital in Berlin.[1]
In 1933, he married Dr. Elsbet Engel, a specialist in
urology.
At the start of World War II, he became a medical officer.
In the course of his service, he rose to the rank of Sergeant-Major, until he was captured and
put into a POW camp. Upon his release, in 1945, he
worked as a lumberjack and then as a country doctor in Schwarzwald with his wife. In 1950, he
began practicing as urologist in Bad Kreuznach[1][2]
During the time of his imprisonment, his paper was read by André Frédéric Cournand and Dickinson W. Richards. They
developed ways of applying his technique to heart disease diagnosis
and research. And, in 1956, the Nobel Prize in
Physiology or Medicine was awarded to Cournand, Richards, and
Forssmann.[1]
After winning the Nobel Prize, he was given the position of
Honorary Professor of Surgery and Urology at the University
of Mainz.[1]
Later, in 1954, he was given the Leibniz Medal of the German
Academy of Sciences. And, in 1961, he became an Honorary Professor at the National University of
Cordoba.[1].
In 1962, he became a member of the Executive Board of the German
Surgical Society. He also became a member of the American College of
Chest Physicians, honorary member of the Swedish Society of
Cardiology, the German Society of Urology, and the German Child
Welfare Association.[1]
He and Elsbet had six children: Klaus Forssmann in 1934, Knut
Forssmann in 1936, Jörg Forssmann in 1938, Wolf Forssmann in 1939
(who was first to isolate the atrial natriuretic peptide), Bernd
Forssmann in 1940 (who helped develop the first clinical lithotriptor), and Renate Forssmann in
1943.[1][2]
He died in Schopfheim,
Germany of heart failure on June 1, 1979.[2]
See also
References
- ^ a
b
c
d
e
f
g
h
i
"Werner Forssmann -
Biography". Nobel Foundation. http://nobelprize.org/nobel_prizes/medicine/laureates/1956/forssmann-bio.html. Retrieved
2008-12-22.
- ^ a
b
c
d
e
"Werner Forssmann". NNDB. http://www.nndb.com/people/706/000129319/. Retrieved
2009-03-31.
- ^ Sanghavi, Darshak (2007-05-08). "Plumber's Butt? The right and wrong way to think
about heart attacks". Slate. http://www.slate.com/id/2165826/.
- ^ "The History of Werner
Forssmann". UTMB. http://www.utmb.edu/forssmann/history_of_werner_forssmann.asp. Retrieved
2008-12-22.
- Goerig, Michael; Agarwal Kamayni
(February 2008). "[Werner Forssmann: "the typical man before his
time!" - self-experiment shows feasibility of cardiac
catheterization]". Anästhesiologie, Intensivmedizin,
Notfallmedizin, Schmerztherapie : AINS
43 (2): 162–5. doi:10.1055/s-2008-1060550. PMID 18293251.
- Hollmann, Wildor (October 2006).
"Werner Forssmann, Eberswalde, the 1956 Nobel Prize for medicine".
Eur. J. Med. Res. 11 (10): 409–12. PMID 17107872.
- Forssmann, Wolf-Georg; Hirsch
Jochen R (October 2006). "50 years Nobel Prize: Werner Forssmann
and the issue of commemorative stamps". Eur. J. Med. Res.
11 (10): 406–8. PMID 17107871.
- Berry, Diana (February 2006).
"History of cardiology: Werner Forssmann, MD". Circulation
113 (7): f27–8. PMID 16493783.
- "[Werner Forssmann tested the
first heart catheter on himself. For this reason he was fired by
the chief physician]". MMW Fortschritte der Medizin
146 (33-34): 56. August 2004. PMID 15526639.
- Bröer, R (October 2002).
"[Legend or reality? - Werner Forssmann and heart
catheterization]". Dtsch. Med. Wochenschr.
127 (41): 2151–4. doi:10.1055/s-2002-34642. PMID 12397563.
- Raju, T N (May 1999). "The Nobel
chronicles. 1956: Werner Forssmann (1904-79); André Frédéric
Cournand (1895-1988); and Dickinson Woodruff Richards, Jr
(1895-1973)". Lancet 353 (9167):
1891. doi:10.1016/S0140-6736(05)75106-0. PMID 10359453.
- Siegel, D (December 1997).
"Werner Forssmann and the Nazis". Am. J. Cardiol.
80 (12): 1643–4. doi:10.1016/S0002-9149(97)00944-2. PMID 9068526.
- Hart, F D (May 1997). "Werner
Forssmann (1904-1979), auto-experimenter/medical martyr. The
original cardiac catheterization". Journal of medical
biography 5 (2): 120–1. PMID 11619092.
- Forssmann-Falck, R (March 1997).
"Werner Forssmann: a pioneer of cardiology". Am. J.
Cardiol. 79 (5): 651–60. doi:10.1016/S0002-9149(96)00833-8. PMID 9416961.
- Heiss, H W (July 1992). "Werner
Forssmann: a German problem with the Nobel Prize". Clinical
cardiology 15 (7): 547–9. doi:10.1002/clc.4960150715. PMID 1499182.
- Meyer, J A (March 1990). "Werner
Forssmann and catheterization of the heart, 1929". Ann. Thorac.
Surg. 49 (3): 497–9. PMID 2178572.
- Schadewaldt, H (December 1979).
"[Werner Forssmann 29.8.1904 - 1.6.1979]". Dtsch. Med.
Wochenschr. 104 (52): 1856–7. PMID 391522.
- Steckelberg, J M; Vlietstra R E,
Ludwig J, Mann R J (November 1979). "Werner Forssmann (1904--1979)
and his unusual success story". Mayo Clin. Proc.
54 (11): 746–8. PMID 386001.
- Asperger, Z (August 1979). "[The
life of Doctor Werner Forssmann (1904--1979) (author's transl)]".
Lijecnicki vjesnik 101 (8): 509–17. PMID 396430.
- "[Münchener Medizinische
Wochenschrift/20 March 1931 Contrast representation of the cavities
of the living right half of the heart by Werner Forssmann,
Eberswalde]". MMW, Münchener medizinische Wochenschrift
120 (14): 489. April 1978. PMID 347275.
- Kenéz, J (December 1969).
"[Heroic self-experiment of a practicing physician (Werner
Forssmann)]". Orvosi hetilap 110 (52):
3069–74. PMID 4904895.
- Sulek, K (January 1969). "[Nobel
prize for Andre F. Cournand, Werner T. O. Forssmann and Dickinson
W. Richards in 1956 for the discovery related to heart
catheterization and studies on pathological changes in the
cardiovascular system]". Wiad. Lek. 22
(2): 203–4. PMID 4890192.
- HEUSCH, K (1957). "[Werner
Forssmann, Nobel prize winner for medicine, 1956.]".
Zeitschrift für Urologie 50 (2): 57–9. PMID 13434311.
- BOLT, W; KNIPPING H W (December
1956). "[Congratulations to Werner Forssmann on winning the 1956
Nobel prize for medicine.]". Med. Klin. (Munich)
51 (49): 2073–6. PMID 13386873.
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