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Xylazine
Systematic (IUPAC) name
N-​(2,6-​dimethylphenyl)-​5,6-​dihydro-​4 H-​1,3-​thiazin-​2-​amine
Identifiers
CAS number 7361-61-7
ATCvet code QN05CM92
PubChem 5707
Chemical data
Formula C 12H16N2S 
Mol. mass 220.33
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status Veterinary Use
Routes  ?
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Xylazine is a drug that is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals. An analogue of clonidine, it is an agonist at the α2 class of adrenergic receptor. As with other α2 agonists, adverse effects include bradycardia, conduction disturbances, and myocardial depression. Yohimbine (Yobine) and atipamezole (commercial name Antisedan) can be used to reverse xylazine effects. In veterinary anesthesia, xylazine is often used in combination with ketamine. No formal information in humans is available. Xylazine is sold by Bayer under the brand name Rompun.

use as emetic in cats

Veterinarians use xylazine as an emetic when it is desirable to remove a substance from a cat's stomach. In one trial, pilocarpine was used instead of xylazine.

References








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