The Full Wiki

More info on ZBTB33

ZBTB33: Wikis


Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.


From Wikipedia, the free encyclopedia

Zinc finger and BTB domain containing 33
Symbols ZBTB33; ZNF-kaiso; ZNF348
External IDs OMIM300329 MGI1927290 HomoloGene4931 GeneCards: ZBTB33 Gene
RNA expression pattern
PBB GE ZBTB33 214631 at tn.png
More reference expression data
Species Human Mouse
Entrez 10009 56805
Ensembl ENSG00000177485 ENSMUSG00000048047
UniProt Q86T24 A0PJC8
RefSeq (mRNA) NM_006777 NM_001079513
RefSeq (protein) NP_006768 NP_001072981
Location (UCSC) Chr X:
119.27 - 119.28 Mb
Chr X:
34.43 - 34.44 Mb
PubMed search [1] [2]

Transcriptional regulator Kaiso is a protein that in humans is encoded by the ZBTB33 gene.[1]



ZBTB33 has been shown to interact with HDAC3,[2] Nuclear receptor co-repressor 1[2] and CTNND1.[3]


  1. ^ "Entrez Gene: ZBTB33 zinc finger and BTB domain containing 33".  
  2. ^ a b Yoon, Ho-Geun; Chan Doug W, Reynolds Albert B, Qin Jun, Wong Jiemin (Sep. 2003). "N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso". Mol. Cell (United States) 12 (3): 723–34. ISSN 1097-2765. PMID 14527417.  
  3. ^ Daniel, J M; Reynolds A B (May. 1999). "The catenin p120(ctn) interacts with Kaiso, a novel BTB/POZ domain zinc finger transcription factor". Mol. Cell. Biol. (UNITED STATES) 19 (5): 3614–23. ISSN 0270-7306. PMID 10207085.  

Further reading

  • Daniel JM, Reynolds AB (1999). "The catenin p120(ctn) interacts with Kaiso, a novel BTB/POZ domain zinc finger transcription factor.". Mol. Cell. Biol. 19 (5): 3614–23. PMID 10207085.  
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMID 11076863.  
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.  
  • Prokhortchouk A, Hendrich B, Jørgensen H, et al. (2001). "The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor.". Genes Dev. 15 (13): 1613–8. doi:10.1101/gad.198501. PMID 11445535.  
  • Daniel JM, Ireton RC, Reynolds AB (2001). "Monoclonal antibodies to Kaiso: a novel transcription factor and p120ctn-binding protein.". Hybridoma 20 (3): 159–66. doi:10.1089/027245701750293484. PMID 11461664.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Yoon HG, Chan DW, Reynolds AB, et al. (2003). "N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso.". Mol. Cell 12 (3): 723–34. doi:10.1016/j.molcel.2003.08.008. PMID 14527417.  
  • Kondapalli J, Flozak AS, Albuquerque ML (2004). "Laminar shear stress differentially modulates gene expression of p120 catenin, Kaiso transcription factor, and vascular endothelial cadherin in human coronary artery endothelial cells.". J. Biol. Chem. 279 (12): 11417–24. doi:10.1074/jbc.M306057200. PMID 14699141.  
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID 15489336.  
  • Kim SW, Park JI, Spring CM, et al. (2005). "Non-canonical Wnt signals are modulated by the Kaiso transcriptional repressor and p120-catenin.". Nat. Cell Biol. 6 (12): 1212–20. doi:10.1038/ncb1191. PMID 15543138.  
  • Ruzov A, Dunican DS, Prokhortchouk A, et al. (2005). "Kaiso is a genome-wide repressor of transcription that is essential for amphibian development.". Development 131 (24): 6185–94. doi:10.1242/dev.01549. PMID 15548582.  
  • Kelly KF, Otchere AA, Graham M, Daniel JM (2005). "Nuclear import of the BTB/POZ transcriptional regulator Kaiso.". J. Cell. Sci. 117 (Pt 25): 6143–52. doi:10.1242/jcs.01541. PMID 15564377.  
  • Rush J, Moritz A, Lee KA, et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.". Nat. Biotechnol. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455.  
  • Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome.". Nature 434 (7031): 325–37. doi:10.1038/nature03440. PMID 15772651.  
  • Soubry A, van Hengel J, Parthoens E, et al. (2005). "Expression and nuclear location of the transcriptional repressor Kaiso is regulated by the tumor microenvironment.". Cancer Res. 65 (6): 2224–33. doi:10.1158/0008-5472.CAN-04-2020. PMID 15781635.  
  • Spring CM, Kelly KF, O'Kelly I, et al. (2005). "The catenin p120ctn inhibits Kaiso-mediated transcriptional repression of the beta-catenin/TCF target gene matrilysin.". Exp. Cell Res. 305 (2): 253–65. doi:10.1016/j.yexcr.2005.01.007. PMID 15817151.  
  • Arányi T, Faucheux BA, Khalfallah O, et al. (2005). "The tissue-specific methylation of the human tyrosine hydroxylase gene reveals new regulatory elements in the first exon.". J. Neurochem. 94 (1): 129–39. doi:10.1111/j.1471-4159.2005.03173.x. PMID 15953356.  
  • Defossez PA, Kelly KF, Filion GJ, et al. (2006). "The human enhancer blocker CTC-binding factor interacts with the transcription factor Kaiso.". J. Biol. Chem. 280 (52): 43017–23. doi:10.1074/jbc.M510802200. PMID 16230345.  

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



Got something to say? Make a comment.
Your name
Your email address