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Zinc finger protein 143
Symbols ZNF143; SBF; STAF; pHZ-1
External IDs OMIM603433 MGI1277969 HomoloGene56444 GeneCards: ZNF143 Gene
RNA expression pattern
PBB GE ZNF143 221873 at tn.png
More reference expression data
Species Human Mouse
Entrez 7702 20841
Ensembl ENSG00000166478 ENSMUSG00000061079
UniProt P52747 Q8CEI6
RefSeq (mRNA) NM_003442 NM_009281
RefSeq (protein) NP_003433 NP_033307
Location (UCSC) Chr 11:
9.44 - 9.51 Mb
Chr 7:
109.85 - 109.89 Mb
PubMed search [1] [2]

Zinc finger protein 143 is a protein that in humans is encoded by the ZNF143 gene.[1]


Further reading

  • Tommerup N, Vissing H (1995). "Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.". Genomics 27 (2): 259–64. doi:10.1006/geno.1995.1040. PMID 7557990.  
  • Schuster C, Myslinski E, Krol A, Carbon P (1995). "Staf, a novel zinc finger protein that activates the RNA polymerase III promoter of the selenocysteine tRNA gene.". Embo J. 14 (15): 3777–87. PMID 7641696.  
  • Schaub M, Myslinski E, Schuster C, et al. (1997). "Staf, a promiscuous activator for enhanced transcription by RNA polymerases II and III.". Embo J. 16 (1): 173–81. doi:10.1093/emboj/16.1.173. PMID 9009278.  
  • Schuster C, Krol A, Carbon P (1998). "Two distinct domains in Staf to selectively activate small nuclear RNA-type and mRNA promoters.". Mol. Cell. Biol. 18 (5): 2650–8. PMID 9566884.  
  • Myslinski E, Krol A, Carbon P (1998). "ZNF76 and ZNF143 are two human homologs of the transcriptional activator Staf.". J. Biol. Chem. 273 (34): 21998–2006. doi:10.1074/jbc.273.34.21998. PMID 9705341.  
  • Rincon JC, Engler SK, Hargrove BW, Kunkel GR (1998). "Molecular cloning of a cDNA encoding human SPH-binding factor, a conserved protein that binds to the enhancer-like region of the U6 small nuclear RNA gene promoter.". Nucleic Acids Res. 26 (21): 4846–52. doi:10.1093/nar/26.21.4846. PMID 9776743.  
  • Mach CM, Hargrove BW, Kunkel GR (2002). "The Small RNA gene activator protein, SphI postoctamer homology-binding factor/selenocysteine tRNA gene transcription activating factor, stimulates transcription of the human interferon regulatory factor-3 gene.". J. Biol. Chem. 277 (7): 4853–8. doi:10.1074/jbc.M108308200. PMID 11724783.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Grossman CE, Qian Y, Banki K, Perl A (2004). "ZNF143 mediates basal and tissue-specific expression of human transaldolase.". J. Biol. Chem. 279 (13): 12190–205. doi:10.1074/jbc.M307039200. PMID 14702349.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Wakasugi T, Izumi H, Uchiumi T, et al. (2007). "ZNF143 interacts with p73 and is involved in cisplatin resistance through the transcriptional regulation of DNA repair genes.". Oncogene 26 (36): 5194–203. doi:10.1038/sj.onc.1210326. PMID 17297437.  
  • Myslinski E, Gérard MA, Krol A, Carbon P (2007). "Transcription of the human cell cycle regulated BUB1B gene requires hStaf/ZNF143.". Nucleic Acids Res. 35 (10): 3453–64. doi:10.1093/nar/gkm239. PMID 17478512.  
  • Gérard MA, Krol A, Carbon P (2007). "Transcription factor hStaf/ZNF143 is required for expression of the human TFAM gene.". Gene 401 (1-2): 145–53. doi:10.1016/j.gene.2007.07.011. PMID 17707600.  
  • Yuan CC, Zhao X, Florens L, et al. (2007). "CHD8 associates with human Staf and contributes to efficient U6 RNA polymerase III transcription.". Mol. Cell. Biol. 27 (24): 8729–38. doi:10.1128/MCB.00846-07. PMID 17938208.  

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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