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Zinc finger protein 239
Symbols ZNF239; HOK-2; MOK2
External IDs OMIM601069 MGI1306812 HomoloGene68480 GeneCards: ZNF239 Gene
RNA expression pattern
PBB GE ZNF239 206261 at tn.png
More reference expression data
Species Human Mouse
Entrez 8187 22685
Ensembl ENSG00000196793 ENSMUSG00000042097
UniProt Q16600 Q99J71
RefSeq (mRNA) NM_005674 NM_001001792
RefSeq (protein) NP_005665 NP_001001792
Location (UCSC) Chr 10:
43.37 - 43.39 Mb
Chr 6:
117.83 - 117.84 Mb
PubMed search [1] [2]

Zinc finger protein 239 is a protein that in humans is encoded by the ZNF239 gene.[1][2][3]

MOK2 proteins are DNA- and RNA-binding proteins that are mainly associated with nuclear RNP components, including the nucleoli and extranucleolar structures (Arranz et al., 1997).[supplied by OMIM][3]



ZNF239 has been shown to interact with LMNA.[4]


  1. ^ Arranz V, Kress M, Ernoult-Lange M (Feb 1997). "Localization of zinc finger Mok2 gene to mouse chromosome 6, a new region of homology with human chromosome 19". Mamm Genome 7 (1): 77–8. PMID 8903737.  
  2. ^ Ernoult-Lange M, Arranz V, Le Coniat M, Berger R, Kress M (Mar 1996). "Human and mouse Kruppel-like (MOK2) orthologue genes encode two different zinc finger proteins". J Mol Evol 41 (6): 784–94. PMID 8587123.  
  3. ^ a b "Entrez Gene: ZNF239 zinc finger protein 239".  
  4. ^ Dreuillet, Caroline; Tillit Jeanne, Kress Michel, Ernoult-Lange Michèle (Nov. 2002). "In vivo and in vitro interaction between human transcription factor MOK2 and nuclear lamin A/C". Nucleic Acids Res. (England) 30 (21): 4634–42. PMID 12409453.  

Further reading

  • Arranz V, Harper F, Florentin Y, et al. (1997). "Human and mouse MOK2 proteins are associated with nuclear ribonucleoprotein components and bind specifically to RNA and DNA through their zinc finger domains.". Mol. Cell. Biol. 17 (4): 2116–26. PMID 9121460.  
  • Dreuillet C, Tillit J, Kress M, Ernoult-Lange M (2002). "In vivo and in vitro interaction between human transcription factor MOK2 and nuclear lamin A/C.". Nucleic Acids Res. 30 (21): 4634–42. doi:10.1093/nar/gkf587. PMID 12409453.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19.". Nature 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.  
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.  

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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