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Zinc finger protein 259
Symbols ZNF259; MGC110983; ZPR1
External IDs OMIM603901 MGI1330262 HomoloGene2900 GeneCards: ZNF259 Gene
Species Human Mouse
Entrez 8882 22687
Ensembl ENSG00000109917 ENSMUSG00000032078
UniProt O75312 Q3TI08
RefSeq (mRNA) NM_003904 NM_011752
RefSeq (protein) NP_003895 NP_035882
Location (UCSC) Chr 11:
116.15 - 116.16 Mb
Chr 9:
46.02 - 46.03 Mb
PubMed search [1] [2]

Zinc finger protein ZPR1 is a protein that in humans is encoded by the ZNF259 gene.[1][2][3]


  1. ^ Galcheva-Gargova Z, Konstantinov KN, Wu IH, Klier FG, Barrett T, Davis RJ (Jul 1996). "Binding of zinc finger protein ZPR1 to the epidermal growth factor receptor". Science 272 (5269): 1797-802. PMID 8650580.  
  2. ^ Galcheva-Gargova Z, Gangwani L, Konstantinov KN, Mikrut M, Theroux SJ, Enoch T, Davis RJ (Nov 1998). "The cytoplasmic zinc finger protein ZPR1 accumulates in the nucleolus of proliferating cells". Mol Biol Cell 9 (10): 2963-71. PMID 9763455.  
  3. ^ "Entrez Gene: ZNF259 zinc finger protein 259".  

Further reading

  • Gangwani L, Mikrut M, Galcheva-Gargova Z, Davis RJ (1999). "Interaction of ZPR1 with translation elongation factor-1alpha in proliferating cells.". J. Cell Biol. 143 (6): 1471–84. doi:10.1083/jcb.143.6.1471. PMID 9852145.  
  • Moores SL, Selfors LM, Fredericks J, et al. (2000). "Vav family proteins couple to diverse cell surface receptors.". Mol. Cell. Biol. 20 (17): 6364–73. doi:10.1128/MCB.20.17.6364-6373.2000. PMID 10938113.  
  • Narayanan U, Ospina JK, Frey MR, et al. (2003). "SMN, the spinal muscular atrophy protein, forms a pre-import snRNP complex with snurportin1 and importin beta.". Hum. Mol. Genet. 11 (15): 1785–95. doi:10.1093/hmg/11.15.1785. PMID 12095920.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Gangwani L, Flavell RA, Davis RJ (2005). "ZPR1 is essential for survival and is required for localization of the survival motor neurons (SMN) protein to Cajal bodies.". Mol. Cell. Biol. 25 (7): 2744–56. doi:10.1128/MCB.25.7.2744-2756.2005. PMID 15767679.  
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.  
  • Guo D, Han J, Adam BL, et al. (2005). "Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress.". Biochem. Biophys. Res. Commun. 337 (4): 1308–18. doi:10.1016/j.bbrc.2005.09.191. PMID 16236267.  
  • Gangwani L (2007). "Deficiency of the zinc finger protein ZPR1 causes defects in transcription and cell cycle progression.". J. Biol. Chem. 281 (52): 40330–40. doi:10.1074/jbc.M608165200. PMID 17068332.  

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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