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Zylofuramine: Wikis


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Systematic (IUPAC) name
(1R)-​N-​ethyl-​2-​phenyl-​1-​[(2 R)-​tetrahydrofuran-​2-​yl]​ethanamine
CAS number 3563-92-6
ATC code none
PubChem 71129
Chemical data
Formula C 15H23N 
Mol. mass 219.32264 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Zylofuramine is a stimulant drug. It was developed in 1961,[1] and was intended for use as an appetite suppressant and for the treatment of senile dementia in the elderly, but there is little information about it and it does not appear to have ever been marketed.[2]

Zylofuramine is legal throughout the world. Its chemical structure has a vague similarity to other N-ethyl substituted stimulant drugs such as ethylamphetamine, but its structure would probably not be close enough for it to be considered a controlled substance analogue.


  1. ^ Clarke, R. L.; Harris, L. S. (1962). "α-Benzyltetrahydrofurfurylamines--a New Series of Psychomotor Stimulants. I". Journal of Medicinal Chemistry 5: 77–95. doi:10.1021/jm01236a010.   edit
  2. ^ Harris LS, Clarke RL, Dembinski JR. Alpha-Benzyltetrahydrofurfurylamines - A new series of Psychomotor Stimulants. III. The Pharmacology of D-Threo Alpha-Benzyl-N-Ethyltetrahydrofurfurylamine (Zylofuramine). Archives Internationales de Pharmacodynamie et de Therapie. 1963 Dec 1;146:392-405.


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